IIES

IIES (Intravenous Immaterial Enhancement Solution) is a powerful, artificial substance used to improve ITB Agents' abilities and aid in focus, and it also shows the most effect among the Seekers. Agent L has described them as also acting as conventional hallucinogens. They were developed by Agent F and his team.

Agents L, V, and Z are well-known users of it, though their supply has been greatly diminished following the Basement Incident.